Oxovanadium(IV) Cyclam and Bicyclam Complexes: Potential CXCR4 Receptor Antagonists
نویسندگان
چکیده
منابع مشابه
Configurationally restricted bismacrocyclic CXCR4 receptor antagonists.
A zinc(II) containing configurationally restricted analogue of bismacrocyclic cyclam-type CXCR4 chemokine receptor antagonists has been synthesized and shown to adopt only one configuration in solution. The single crystal X-ray structure reveals favorable binding to acetate via a bidentate chelation that can be related to the proposed interaction with aspartate on the receptor protein surface. ...
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ژورنال
عنوان ژورنال: Inorganic Chemistry
سال: 2009
ISSN: 0020-1669,1520-510X
DOI: 10.1021/ic9020614